Science Briefing

Highlights from the frontiers of biology, medicine, materials, and the mind.

AI Refines CRISPR-Cas13d for Safer RNA Editing

Researchers at the Arc Institute have used deep learning to bring new precision to RNA-targeting CRISPR systems.
By testing more than 127,000 CasRx guides, the team trained a model that predicts guide efficiency across different human cell types — and extended it to a new enzyme, DjCas13d, which shows high sp…